An illustrative, non-limiting method for resolving Region-On-Interest (ROI) overlaps includes receiving Simultaneous Localization and Mapping (SLAM) data obtained by a plurality of co-located Head-Mounted Devices (HMD), where the SLAM data comprises a plurality of landmarks and each HMD has an Information Handling System (IHS) in communication therewith. Each IHS may produce a subset of the plurality of landmarks based upon a respective HMD's SLAM data, and each IHS is: local with respect to the plurality of HMDs, at an edge of a network serving an HMD, or on a cloud. The method may include identifying an overlap between a first landmark produced by a first IHS and a second landmark produced by a second IHS, selecting between the first and second landmarks, at least in part, based upon the locations of the first and second IHSs, and rendering a map for display by a given HMD using the selected landmark.