Invention Grant
- Patent Title: Robust broad beam optimization for proton therapy
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Application No.: US16301747Application Date: 2017-06-14
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Publication No.: US11052264B2Publication Date: 2021-07-06
- Inventor: Vaitheeswaran Ranganathan , Gipson Joe Anto , Murali Balasubramanian , Bojarajan Perumal , Reshmi Bhattacharjee
- Applicant: KONINKLIJKE PHILIPS N.V.
- Applicant Address: NL Eindhoven
- Assignee: KONINKLIJKE PHILIPS N.V.
- Current Assignee: KONINKLIJKE PHILIPS N.V.
- Current Assignee Address: NL Eindhoven
- International Application: PCT/EP2017/064524 WO 20170614
- International Announcement: WO2017/216219 WO 20171221
- Main IPC: A61N5/10
- IPC: A61N5/10 ; G21K5/04

Abstract:
A robustness optimization is disclosed for a broad beam proton therapy plan. A nominal dose distribution (62) is computed, to be delivered to a volume by performing proton therapy on the volume according to a proton therapy plan (50) having parameters (52) defining a range compensator shape and a range band. The parameters of the proton therapy plan are adjusted to reduce a difference between the nominal dose distribution (62) and a perturbed dose distribution calculated to be delivered to the volume modified by an error scenario (64) by performing proton therapy on the volume modified by the error scenario in accordance with the proton therapy plan with the parameters adjusted by the adjusting operation. The adjusting may be repeated serially for each error scenario of a set of error scenarios (44) to produce a proton therapy plan that is robust for any of these error scenarios.
Public/Granted literature
- US20190290931A1 ROBUST BROAD BEAM OPTIMIZATION FOR PROTON THERAPY Public/Granted day:2019-09-26
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