- Patent Title: Optically active pyrrolidine compound and method for producing same
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Application No.: US16651049Application Date: 2018-09-28
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Publication No.: US11053217B2Publication Date: 2021-07-06
- Inventor: Joji Tsurumoto , Kenji Morokuma
- Applicant: MITSUBISHI TANABE PHARMA CORPORATION
- Applicant Address: JP Osaka
- Assignee: MITSUBISHI TANABE PHARMA CORPORATION
- Current Assignee: MITSUBISHI TANABE PHARMA CORPORATION
- Current Assignee Address: JP Osaka
- Agency: Birch, Stewart, Kolasch & Birch, LLP
- Priority: JPJP2017-190331 20170929
- International Application: PCT/JP2018/036225 WO 20180928
- International Announcement: WO2019/065954 WO 20190404
- Main IPC: C07D401/14
- IPC: C07D401/14

Abstract:
The present invention provides: a methyl 1-{2-[(3S,4R)-1-[(3R,4R)-1-cyclopentyl-3-fluoro-4-(4-methoxyphenyl)pyrrolidine-3-carbonyl]-4-(methoxymethyl)pyrrolidin-3-yl]-5-(trifluoromethyl)phenyl}piperidine-4-carboxylate 1/2 ethane-1,2-disulfonic acid which is represented by formula (1) and is excellent in crystallinity; and a method for producing the same; and a production intermediate thereof; and a production method using this compound.
Public/Granted literature
- US20200239440A1 OPTICALLY ACTIVE PYRROLIDINE COMPOUND AND METHOD FOR PRODUCING SAME Public/Granted day:2020-07-30
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