Invention Grant
- Patent Title: Substituted pyrimidines for inhibiting embryonic leucine zipper kinase activity
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Application No.: US16664649Application Date: 2019-10-25
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Publication No.: US11053221B2Publication Date: 2021-07-06
- Inventor: Hariprasad Vankayalapati
- Applicant: Arrien Pharmaceuticals LLC
- Applicant Address: US UT Salt Lake City
- Assignee: Arrien Pharmaceuticals LLC
- Current Assignee: Arrien Pharmaceuticals LLC
- Current Assignee Address: US UT Salt Lake City
- Agency: Seed IP Law Group LLP
- Main IPC: A61K31/506
- IPC: A61K31/506 ; C07D239/24 ; C07D403/04 ; A61P35/02 ; C07D401/14

Abstract:
Compounds having activity as chemotherapeutic agents are provided. The compounds have the following structure (I): or a pharmaceutically acceptable salt, stereoisomer, isotopic form or prodrug thereof, wherein R1a, R1b, R1c, R1d, L, and are as defined herein. Methods associated with preparation and use of such compounds, pharmaceutical compositions comprising such compounds and methods for treating cancer (e.g., hematological cancers) are also provided.
Information query
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