Invention Grant
- Patent Title: Methods and systems for converting precursor cells into gastric tissues through directed differentiation
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Application No.: US16188597Application Date: 2018-11-13
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Publication No.: US11053477B2Publication Date: 2021-07-06
- Inventor: James Macormack Wells , Kyle William McCracken
- Applicant: Children's Hospital Medical Center
- Applicant Address: US OH Cincinnati
- Assignee: Children's Hospital Medical Center
- Current Assignee: Children's Hospital Medical Center
- Current Assignee Address: US OH Cincinnati
- Agency: Knobbe, Martens, Olson & Bear, LLP
- Main IPC: C12N5/071
- IPC: C12N5/071
Abstract:
Disclosed are methods of inducing formation of a gastric cells and/or a gastric tissue, such as in the form of a gastric organoid. The formation of gastric cells and/or tissue may be carried out by the activating and/or inhibiting of one or more signaling pathways within a precursor cell. Also disclosed are methods for using the disclosed gastric cells, gastric tissues, and/or gastric organoids derived from precursor cells.
Public/Granted literature
- US20190153397A1 METHODS AND SYSTEMS FOR CONVERTING PRECURSOR CELLS INTO GASTRIC TISSUES THROUGH DIRECTED DIFFERENTIATION Public/Granted day:2019-05-23
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