Pickling a plurality of steel strips (2) having initial material properties (ME) on a pickling line: A computer (5) defines a number of sequences (Gi), which each contain the number of strips (2) to be pickled. For each of the defined sequences (Gi), the computer (5) determines an optimized mode of operation of the pickling line and, on the basis of the mode of operation, at least one measure (M), by means of a model (9) of the pickling line based on mathematical physical equations and by using the initial material properties (ME) of the strips. As long as a termination criterion (K) is not met, the computer (5) varies the defined sequences (Gi) and determines respective optimized modes of operation of the pickling line and associated measures (M) anew. As soon as the termination criterion (K) is met, the computer (5) either selects one of the last defined sequences (Gi) and initiates the control of the pickling line in accordance with the selected sequence (Gi) or offers to an operator (13) a plurality of the last defined sequences (Gi) together with the respective measures (M) thereof, receives a selection command (SEL) for selecting one of the offered sequences (Gi) from the operator (13), and initiates the control of the pickling line in accordance with the sequence (Gi) selected from the operator (13).