A system (10) delivers of a flowable substance S to a remote location through a conduit (144). The system (10) has a body 12 with first and second portions (14,16) and at least two plugs (P1, P2) associated with the body (12) so that in a first configuration the plugs (P1, P2) are spaced apart and form a sealed region (20) for holding a volume of the substance S, and, in a second configuration at least the second plug (P2) is disposed in the second portion wherein the substance S can flow in a downstream direction past or through the second plug and out of the body (12). A first valve (66) is coupled with the body (12) and has: (a) and opened state where the substance S is able to flow out of the body (12) and (b) a closed state where the first valve (66) prevents flow of the substance S out of the body (12) and prevents flow of a further fluid into or out of the body (12) while allowing a bypass flow of the further fluid in an upstream direction through a bypass flow path (110) of the first valve (66) to facilitate travel of the system (10) through a column of the further fluid in the conduit (144).