A portable safety control device for use with a portable electronic device to communicate with an industrial machine. The control device includes a body having gripping portion for engagement by a human hand and a supporting portion for engagement with the portable electronic device. In one example, separate enabling and emergency stop switches are positioned on the body proximate the gripping portion within reach of the hand engaged with the gripping portion, and is configured for ease of use by left or right-handed users. The supporting portion is configured and oriented to rest on the forearm of an operator. A control circuit is used to communicate with both the portable electronic device and the industrial machine controller.