Methods and systems for multimodal motion planning framework for autonomous driving vehicles are disclosed. In one embodiment, driving environment data of an autonomous vehicle is received, where the environment data includes a route segment. The route segment is segmented into a number of route sub-segments. A specific driving scenario is assigned to each of the route sub-segments, where each specific driving scenario is included in a set of driving scenarios. A first motion planning algorithm is assigned according to a first assigned driving scenario included in the set of driving scenarios. The first motion planning algorithm is invoked to generate a first set of trajectories. The autonomous vehicle is controlled based on the first set of trajectories.