A variety of graphically responsive defibrillation electrode pads are described that can selectively display different images during use. The graphically responsive pads include a base electrode pad structure, at least two graphics, and one or more controllable layers that have multiple states. In some embodiments, the controllable layer incorporates an electrochromic material. In a first (opaque) state, the controllable layer hides the first graphic such that only the second graphic is visible to a user on the back side of the defibrillation electrode pad. When the controllable layer transitions to a second (transparent) state, the first graphic is made visible to thereby cause a composite image that combines the first and second graphics to be visible on the back side of the pad. In some embodiments, the electrochromic layer defaults to the opaque state when no power is applied to the electrochromic layer.