Invention Grant
![Aryl dihydro-2H benzo[b][1,4]oxazine sulfonamide and related compounds for use as agonists of RORγ and the treatment of disease](/docs/US/2021-07-13/US11059796B2/abs.jpg.600x600.jpg)
- Patent Title: Aryl dihydro-2H benzo[b][1,4]oxazine sulfonamide and related compounds for use as agonists of RORγ and the treatment of disease
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Application No.: US16812538Application Date: 2020-03-09
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Publication No.: US11059796B2Publication Date: 2021-07-13
- Inventor: Thomas Daniel Aicher , Clarke B. Taylor , Chad A. VanHuis
- Applicant: The Regents of the University of Michigan
- Applicant Address: US MI Ann Arbor
- Assignee: The Regents of the University of Michigan
- Current Assignee: The Regents of the University of Michigan
- Current Assignee Address: US MI Ann Arbor
- Agency: Dechert LLP
- Main IPC: C07D265/36
- IPC: C07D265/36 ; C07D413/14 ; C07D215/58 ; C07D413/06 ; C07D413/12 ; C07D417/14 ; C07D471/04 ; C07D413/04 ; C07D417/12 ; C07D279/16 ; C07D417/04 ; A61P35/00 ; C07D413/10 ; C07D417/06 ; C07D417/10
![Aryl dihydro-2H benzo[b][1,4]oxazine sulfonamide and related compounds for use as agonists of RORγ and the treatment of disease](/abs-image/US/2021/07/13/US11059796B2/abs.jpg.150x150.jpg)
Abstract:
The invention provides aryl dihydro-2H-benzo[b][1,4]oxazine sulfonamide and related compounds, pharmaceutical compositions, methods of promoting RORγ activity, methods of increasing the amount of IL-17 in a subject, and methods of treating cancer and other medical disorders using such compounds.
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