Invention Grant
- Patent Title: Difluoroketamide derivatives as HtrA1 inhibitors
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Application No.: US16121244Application Date: 2018-09-04
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Publication No.: US11059858B2Publication Date: 2021-07-13
- Inventor: Hans P. Maerki , Benoit Hornsperger , Peter Mohr , Michael Reutlinger , Roberto Iacone
- Applicant: Hoffmann-La Roche Inc.
- Applicant Address: US NJ Little Falls
- Assignee: Hoffmann-La Roche Inc.
- Current Assignee: Hoffmann-La Roche Inc.
- Current Assignee Address: US NJ Little Falls
- Agent Bradley E. Davis
- Priority: EP16158644 20160304
- Main IPC: C07K5/083
- IPC: C07K5/083 ; C07K5/08 ; C07K5/087 ; C07K5/093 ; C07K5/103 ; C07K5/09 ; C07K5/065 ; C07K5/062 ; C07K5/06

Abstract:
The invention provides novel compounds having the general formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11 and R23 are as described herein, compositions including the compounds and methods of using the compounds.
Public/Granted literature
- US20180371015A1 NEW DIFLUOROKETAMIDE DERIVATIVES AS HTRA1 INHIBITORS Public/Granted day:2018-12-27
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