- Patent Title: Therapeutic targeting of SET1B/compass pathway for treating cancers
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Application No.: US16355124Application Date: 2019-03-15
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Publication No.: US11059878B2Publication Date: 2021-07-13
- Inventor: Ali Shilatifard , Lu Wang
- Applicant: Northwestern University
- Applicant Address: US IL Evanston
- Assignee: Northwestern University
- Current Assignee: Northwestern University
- Current Assignee Address: US IL Evanston
- Agency: Quarles & Brady LLP
- Main IPC: C07K14/575
- IPC: C07K14/575 ; C07K14/47 ; C07K7/06 ; C07K16/30 ; A61K38/22 ; C12Q1/6886 ; C12N15/113
Abstract:
Disclosed are methods for treating Set1/COMPASS-associated cancers characterized by expression of Set1B/COMPASS. The methods typically include administering a therapeutic amount of an inhibitor of the Set1B/COMPASS pathway and/or an agonist for a target that is negatively regulated by the Set1B/COMPASS pathway.
Public/Granted literature
- US20200223895A1 THERAPEUTIC TARGETING OF SET1B/COMPASS PATHWAY FOR TREATING CANCERS Public/Granted day:2020-07-16
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