Invention Grant
- Patent Title: Anti-IFNAR1 antibodies for treating autoimmune diseases
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Application No.: US16963128Application Date: 2019-09-18
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Publication No.: US11059897B2Publication Date: 2021-07-13
- Inventor: Wei Cao , Weili Xu
- Applicant: I-Mab Biopharma US Limited
- Applicant Address: US MD Gaithersburg
- Assignee: I-Mab Biopharma US Limited
- Current Assignee: I-Mab Biopharma US Limited
- Current Assignee Address: US MD Gaithersburg
- Agency: Sheppard Mullin Richter & Hampton LLP
- Priority: WOPCT/CN2018/106157 20180918
- International Application: PCT/CN2019/106412 WO 20190918
- International Announcement: WO2020/057541 WO 20200326
- Main IPC: C07K16/28
- IPC: C07K16/28 ; A61K39/00 ; G01N33/53
Abstract:
Provided are antibodies or fragments thereof having binding specificity to the human interferon alpha and beta receptor subunit 1 (IFNAR1) protein. In various examples, the antibodies or fragments thereof include a VH and VL CDRs as provided, or variants thereof. Methods of using the antibodies or fragments thereof for treating autoimmune diseases and disorders are also provided.
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