Provided is an abrasion-resistant steel plate which has high hardness up to the mid-thickness part thereof although the steel plate is 50 mm or more, and can be manufactured at low cost. The abrasion-resistant steel plate has a specific chemical composition having DI* of 120 or more, where DI* is defined by the following Formula (1): DI*=33.85×(0.1×C)0.5×(0.7×Si+1)×(3.33×Mn+1)×(0.35×Cu+1)×(0.36×Ni+1)×(2.16×Cr+1)×(3×Mo+1)×(1.75×V+1)×(1.5×W+1) . . . (1), has HB1 of 360 HBW10/3000 to 490 HBW10/3000, HB1 being a Brinell hardness at a depth of 1 mm from a surface, has a hardness ratio, HB1/2 to HB1, of 75% or more, HB1/2 being a Brinell hardness at a mid-thickness position, and has a plate thickness of 50 mm or more.