A system and method for reconstructing an image of a subject acquired using a tomographic imaging system includes at least one computer processor configured to form an image reconstruction pipeline. The reconstruction pipeline at least includes an automated correction module configured to receive imaging data acquired from a subject using ionizing radiation generated by the tomographic imaging system and generate corrected data using a first learning network. The reconstruction pipeline also includes an intelligent reconstruction module configured to receive at least one of the imaging data and the corrected data and reconstruct an image of the subject using a second learning network.