Embodiments herein relate to a method performed by a network node (13) for handling communication of a wireless device (10) in a wireless communication network (1). The network node (13), such as an MME, pages the wireless device (10) using a first paging channel; and pages the wireless device (10) using a second paging channel, wherein paging the wireless device (10) using the first paging channel comprises selecting one or more radio network nodes to page the wireless device (10) using the first paging channel based on information relating to current knowledge of a location of the wireless device (10).