An anti-counterfeiting tag, system and method of manufacturing and authentication therefor are provided. The tag comprises a substrate; and a plurality of layers printed on at least a portion of the substrate; wherein one of said plurality of layers is configured to generate a self-forming three dimensional (3D) raised random pattern comprising physically unclonable function (PUF) and the other layers are configured to facilitate formation of the 3D pattern and/or to protect the formed 3D pattern.