Invention Grant
- Patent Title: Tetrahydroquinoline derivatives as P2X7 receptor antagonists
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Application No.: US16491119Application Date: 2018-03-13
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Publication No.: US11077100B2Publication Date: 2021-08-03
- Inventor: Hirohide Noguchi , Yoshimasa Arano , Kazuo Ando , Kazuki Toyoshima , Toshihiko Sone
- Applicant: RaQualia Pharma Inc. , Asahi Kasei Pharma Corporation
- Applicant Address: JP Nagoya; JP Tokyo
- Assignee: RaQualia Pharma Inc.,Asahi Kasei Pharma Corporation
- Current Assignee: RaQualia Pharma Inc.,Asahi Kasei Pharma Corporation
- Current Assignee Address: JP Nagoya; JP Tokyo
- Agent Nelsen L. Lentz
- Priority: JPJP2017-047794 20170313
- International Application: PCT/JP2018/009627 WO 20180313
- International Announcement: WO2018/168818 WO 20180920
- Main IPC: A61K31/47
- IPC: A61K31/47 ; C07D215/06
Abstract:
The present invention relates to tetrahydroquinoline derivatives of the present invention or a pharmaceutically acceptable salt thereof or a prodrug thereof, processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of various disorders which are mediated via the P2X7 receptor.
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