Invention Grant
- Patent Title: Isoxazole derivatives as inducers of fetal hemoglobin in erythroid precursor cells from beta-thalassemic patients
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Application No.: US16631295Application Date: 2018-07-13
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Publication No.: US11077116B2Publication Date: 2021-08-03
- Inventor: Ilaria Lampronti , Roberto Gambari , Daniele Simoni
- Applicant: RARE PARTNERS SRL
- Applicant Address: IT Milan
- Assignee: RARE PARTNERS SRL
- Current Assignee: RARE PARTNERS SRL
- Current Assignee Address: IT Milan
- Agency: Silvia Salvadori, P.C.
- Agent Silvia Salvadori
- Priority: IT102017000081419 20170718
- International Application: PCT/EP2018/069158 WO 20180713
- International Announcement: WO2019/016103 WO 20190124
- Main IPC: A61K31/5377
- IPC: A61K31/5377 ; A61K31/42 ; A61P7/06
Abstract:
The invention refers to the use of isoxazole derivatives to prepare medicament able to induce fetal hemoglobin (HbF) synthesis in β-thalassemia and sickle cell disease (SCD) patients.
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