Invention Grant
- Patent Title: Process for the preparation of Deferasirox
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Application No.: US16632318Application Date: 2018-07-02
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Publication No.: US11078167B2Publication Date: 2021-08-03
- Inventor: Hero Velladurai , Janardhana Rao Vascuri , Ravi Shankar Sathu , Sivakumaran Meenakshisunderam
- Applicant: AUROBINDO PHARMA LIMITED , Hero Velladurai , Janardhana Rao Vascuri , Ravi Shankar Sathu , Sivakumaran Meenakshisunderam
- Applicant Address: IN Hyderabad; IN Hyderabad; IN Hyderabad; IN Hyderabad; IN Hyderabad
- Assignee: AUROBINDO PHARMA LIMITED,Hero Velladurai,Janardhana Rao Vascuri,Ravi Shankar Sathu,Sivakumaran Meenakshisunderam
- Current Assignee: AUROBINDO PHARMA LIMITED,Hero Velladurai,Janardhana Rao Vascuri,Ravi Shankar Sathu,Sivakumaran Meenakshisunderam
- Current Assignee Address: IN Hyderabad; IN Hyderabad; IN Hyderabad; IN Hyderabad; IN Hyderabad
- Agent Jay R. Akhave
- Priority: IN201741025653 20170719
- International Application: PCT/IB2018/054902 WO 20180702
- International Announcement: WO2019/016637 WO 20190124
- Main IPC: C07D249/08
- IPC: C07D249/08 ; C07D265/22
Abstract:
The present invention provides an improved process for the preparation of Deferasirox of Formula-I substantially free from ‘hydrazino impurity’ by the condensation of 2-(2-hydrophenyl)-4H-1,3-benzoxazin-4-one of Formula-IV with 4-hydrazino benzoic acid of Formula-V in a polar solvent.
Public/Granted literature
- US20200207725A1 A process for the preparation of Deferasirox Public/Granted day:2020-07-02
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