Invention Grant
- Patent Title: Sulphamoylpyrrolamide derivatives and the use thereof as medicaments for the treatment of hepatitis B
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Application No.: US15117146Application Date: 2015-02-05
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Publication No.: US11078193B2Publication Date: 2021-08-03
- Inventor: Koen Vandyck , Geerwin Yvonne Paul Haché , Stefaan Julien Last , Geert Rombouts , Wim Gaston Verschueren , Pierre Jean-Marie Bernard Raboisson
- Applicant: Janssen Sciences Ireland UC
- Applicant Address: IE Little Island, Co Cork
- Assignee: Janssen Sciences Ireland UC
- Current Assignee: Janssen Sciences Ireland UC
- Current Assignee Address: IE Little Island, Co Cork
- Priority: EP14154167 20140206,EP14169438 20140522,EP14177505 20140717,EP14193926 20141119
- International Application: PCT/EP2015/052389 WO 20150205
- International Announcement: WO2015/118057 WO 20150813
- Main IPC: C07D401/12
- IPC: C07D401/12 ; A61K31/4439 ; C07D405/14 ; A61K31/4545 ; A61K45/06 ; C07D401/14
Abstract:
Inhibitors of HBV replication of Formula (A) including stereochemically isomeric forms, and salts, hydrates, solvates thereof, wherein Ra to Rd, and R5 to R6 have the meaning as defined herein. The present invention also relates to processes for preparing said compounds, pharmaceutical compositions containing them and their use, alone or in combination with other HBV inhibitors, in HBV therapy.
Public/Granted literature
- US20160347741A1 SULPHAMOYLPYRROLAMIDE DERIVATIVES AND THE USE THEREOF AS MEDICAMENTS FOR THE TREATMENT OF HEPATITIS B Public/Granted day:2016-12-01
Information query
