Invention Grant
- Patent Title: Bisaryl amides as NRF2 activators
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Application No.: US16467538Application Date: 2017-12-11
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Publication No.: US11078216B2Publication Date: 2021-08-03
- Inventor: James Francis Callahan , Vincent J. Colandrea , Anthony William James Cooper , Nicole Cathleen Goodwin , Chelsea Ariane Huff , Joel Karpiak , Jeffrey K. Kerns , Hong Nie
- Applicant: GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED
- Applicant Address: GB Brentford
- Assignee: GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED
- Current Assignee: GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED
- Current Assignee Address: GB Brentford
- Agent Nora L. Stein; Fang Qian; Duke M. Fitch
- International Application: PCT/IB2017/057805 WO 20171211
- International Announcement: WO2018/109647 WO 20180621
- Main IPC: A61K31/554
- IPC: A61K31/554 ; A61K31/553 ; A61P1/16 ; A61P9/00 ; A61P11/00 ; A61P11/06 ; A61P13/12 ; A61P17/06 ; A61P35/00 ; C07D281/02 ; C07D417/06 ; C07D417/12 ; C07D417/14 ; C07D419/06 ; C07D419/12 ; C07D419/14 ; C07D513/04 ; C07D515/04 ; C07D401/14
Abstract:
The present invention relates to bisaryl amide analogs, pharmaceutical compositions containing them and their use as NRF2 activators. In particular, the invention relates to bisaryl heterocycles of Formula (I),
Public/Granted literature
- US20190330238A1 BISARYL AMIDES AS NRF2 ACTIVATORS Public/Granted day:2019-10-31
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