Invention Grant
- Patent Title: Thiol compounds and the use thereof for the synthesis of modified oligonucleotides
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Application No.: US15862485Application Date: 2018-01-04
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Publication No.: US11078229B2Publication Date: 2021-08-03
- Inventor: François Morvan , Albert Meyer , Jean-Jacques Vasseur , Julie Mayen , Carole Chaix , Carole Farre , Chantal Fournier-Wirth , Jean-François Cantaloube , Myriam Lereau
- Applicant: Etablissement Français du Sang , Centre National de la Recherche Scientifique (CNRS)
- Applicant Address: FR La Plaine Saint Denis; FR Paris
- Assignee: Etablissement Français du Sang,Centre National de la Recherche Scientifique (CNRS)
- Current Assignee: Etablissement Français du Sang,Centre National de la Recherche Scientifique (CNRS)
- Current Assignee Address: FR La Plaine Saint Denis; FR Paris
- Agency: Stites & Harbison, PLLC
- Agent B. Aaron Schulman, Esq.
- Priority: FR1253121 20120404
- Main IPC: C07H21/04
- IPC: C07H21/04 ; C12N15/11 ; C07F9/24 ; C07C323/52 ; C08F257/02
Abstract:
The present invention relates to a thiol compound suitable for forming a chain of oligomers that can be grafted to an oligonucleotide. The invention also relates to an oligonucleotide grafted by such a compound, thus having one or more thiol functions, suitable for being immobilized on a gold surface or on a grafted surface.
Public/Granted literature
- US20180265538A1 THIOL COMPOUNDS AND THE USE THEREOF FOR THE SYNTHESIS OF MODIFIED OLIGONUCLEOTIDES Public/Granted day:2018-09-20
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