Invention Grant
- Patent Title: Peptides binding to Bfl-1
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Application No.: US15752358Application Date: 2016-08-26
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Publication No.: US11078246B2Publication Date: 2021-08-03
- Inventor: Loren D. Walensky , Gregory H. Bird
- Applicant: Dana-Farber Cancer Institute, Inc.
- Applicant Address: US MA Boston
- Assignee: Dana-Farber Cancer Institute, Inc.
- Current Assignee: Dana-Farber Cancer Institute, Inc.
- Current Assignee Address: US MA Boston
- Agency: Fish & Richardson P.C.
- International Application: PCT/US2016/049095 WO 20160826
- International Announcement: WO2017/040329 WO 20170309
- Main IPC: A61K38/17
- IPC: A61K38/17 ; C07K14/47 ; A61K47/54 ; A61P35/00 ; A61K45/06 ; C12Q1/6886 ; A61K38/00
Abstract:
This disclosure features stapled peptide inhibitors (e.g., cysteine-reactive stapled peptides) of the anti-apoptotic protein, BFL-1, and methods of using same in the treatment of BFL-1 expressing cancers.
Public/Granted literature
- US20190002514A1 PEPTIDES BINDING TO BFL-1 Public/Granted day:2019-01-03
Information query
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