Invention Grant
- Patent Title: CD80 variant immunomodulatory proteins and uses thereof
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Application No.: US16088802Application Date: 2017-04-14
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Publication No.: US11078282B2Publication Date: 2021-08-03
- Inventor: Ryan Swanson , Michael Kornacker
- Applicant: ALPINE IMMUNE SCIENCES, INC.
- Applicant Address: US WA Seattle
- Assignee: ALPINE IMMUNE SCIENCES, INC.
- Current Assignee: ALPINE IMMUNE SCIENCES, INC.
- Current Assignee Address: US WA Seattle
- Agency: Morrison & Foerster LLP
- International Application: PCT/US2017/027817 WO 20170414
- International Announcement: WO2017/181152 WO 20171019
- Main IPC: C07K16/28
- IPC: C07K16/28 ; C07K14/705 ; C12N15/62 ; A61K47/65 ; A61K47/68 ; A61K47/64 ; A61K35/768 ; C12N15/85 ; A61P37/00 ; A61P35/00 ; A61K38/17

Abstract:
Provided herein are variant CD80 polypeptides, immunomodulatory proteins comprising variant CD80 polypeptides, and nucleic acids encoding such proteins. The immunomodulatory proteins provide therapeutic utility for a variety of immunological and oncological conditions. Compositions and methods for making and using such proteins are provided.
Public/Granted literature
- US20190135922A1 CD80 VARIANT IMMUNOMODULATORY PROTEINS AND USES THEREOF Public/Granted day:2019-05-09
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