Invention Grant
- Patent Title: Use of semaphorin-4D inhibitory molecules with an immune modulating therapy to inhibit tumor growth and metastases
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Application No.: US16392451Application Date: 2019-04-23
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Publication No.: US11078295B2Publication Date: 2021-08-03
- Inventor: Elizabeth Evans , Ernest S. Smith , Maurice Zauderer
- Applicant: Vaccinex, Inc.
- Applicant Address: US NY Rochester
- Assignee: Vaccinex, Inc.
- Current Assignee: Vaccinex, Inc.
- Current Assignee Address: US NY Rochester
- Agency: Kacvinsky Daisak Bluni, PLLC
- Main IPC: A61P35/00
- IPC: A61P35/00 ; A61K39/395 ; G01N33/50 ; C07K16/28 ; A61P37/04 ; C07K16/32 ; A61K31/675 ; C07K16/40 ; A61K35/15 ; A61K38/20 ; C07K16/30 ; C12N5/0783 ; C07K14/47 ; C07K16/18 ; C07K14/705 ; A61K39/00
Abstract:
Provided herein are methods for inhibiting, delaying, or reducing tumor growth and metastases of Plexin-B1-expressing cancer cells in a subject, comprising administering to the subject an effective amount of an isolated binding molecule which specifically binds to semaphorin-4D (SEMA4D) in combination with an effective amount of at least one other immune modulating therapy.
Public/Granted literature
Information query
IPC分类:
| A | 人类生活必需 |
| A61 | 医学或兽医学；卫生学 |
| A61P | 化合物或药物制剂的特定治疗活性 |
| A61P35/00 | 抗肿瘤药 |
