A thermoplastic resin composition and a molded article formed using the same. The thermoplastic resin composition includes: a polycarbonate resin; a first polycarbonate-polysiloxane copolymer resin; a second polycarbonate-polysiloxane copolymer resin; and a glycol-modified polyester resin, wherein the first polycarbonate-polysiloxane copolymer resin includes a polysiloxane block having an average degree of polymerization of about 30 to about 45 and the second polycarbonate-polysiloxane copolymer resin includes a polysiloxane block having an average degree of polymerization of about 70 to about 100. The thermoplastic resin composition can have good properties in terms of transparency, impact resistance, chemical resistance, and/or hydrolysis resistance.