A high-strength steel sheet exhibiting excellent ductility and stretch-flangeability, and a method for manufacturing such a high-strength steel sheet. The high-strength steel sheet has a chemical composition including specific proportions of components in which C/Mn is 0.08 to 0.20, the balance being iron and inevitable impurities, and includes microstructures including, in terms of area fraction relative to all the microstructures, 40% to 70% total of ferrite and bainitic ferrite, 5% to 35% martensite and 5% to 30% retained austenite. The proportion of martensite (including retained austenite) adjacent to bainitic ferrite is not less than 60% of all martensite (including retained austenite). The proportion of 4.0 GPa and smaller differences in microhardness measured at 0.5 μm intervals is not less than 70%. The proportion of microstructures with 8.0 GPa or smaller microhardness is not less than 85% of all the microstructures.