A hydrogen station operation method capable of adjusting pressure in a reservoir to the pressure suitable for liquid hydrogen replenishment while cutting hydrogen waste is for replenishing liquid hydrogen into the reservoir in a hydrogen station including: a gasification path partially gasifying liquid hydrogen out of the reservoir and returning it; and a gas delivery path delivering gasified hydrogen in the reservoir into a path between a vaporizer and a compressor or the vaporizer, when the remainder of liquid hydrogen in the reservoir becomes a first threshold or less, by reducing the liquid hydrogen amount flowing through the gasification path by a valve therein, reducing the gasification amount of liquid hydrogen in the reservoir, and increasing the hydrogen gas amount delivered through the gas delivery path from the reservoir by a valve therein, pressure in the reservoir is reduced, thereby performing operation where suction pressure of the compressor is reduced.