A method determining a degree of similarity between a first sample and a second sample, comprising using a processor to compare a first thermogram and a second thermogram, each obtained by performing scanning calorimetry on a first and second sample respectively, by: determining a smoothed first thermogram and a smoothed second thermogram by respectively performing a smoothing operation on the first thermogram and the second thermogram; determining a processed first thermogram and a processed second thermogram by respectively finding a derivative of the smoothed first thermogram and the smoothed second thermogram; determining the degree of similarity from a correlation operation comparing the processed first thermogram with the processed second thermogram.