A method for determining a touch layer pattern, a touch display device, a computer device and a storage medium are provided. The method includes: providing a pixel pattern which contains a light shielding region and a sub-pixel region defined by the light shielding region; superimposing at least two different touch patterns with the pixel pattern respectively to obtain at least two superimposed patterns; and determining, as a touch layer pattern, a touch pattern from the at least two touch patterns, according to equivalent grayscales of the at least two superimposed patterns.