Invention Grant
- Patent Title: Extracellular matrix metalloproteinase inducer (EMMPRIN) peptides and binding antibodies
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Application No.: US16432212Application Date: 2019-06-05
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Publication No.: US11081235B2Publication Date: 2021-08-03
- Inventor: Michal A. Rahat , Nitza Lahat , Miriam Walter , Haim Bitterman
- Applicant: MOR-RESEARCH APPLICATIONS LTD. , TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD.
- Applicant Address: IL Tel Aviv; IL Haifa
- Assignee: MOR-RESEARCH APPLICATIONS LTD.,TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD.
- Current Assignee: MOR-RESEARCH APPLICATIONS LTD.,TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD.
- Current Assignee Address: IL Tel Aviv; IL Haifa
- Agency: J.A. Lindeman & Co., PLLC
- Main IPC: A61K39/00
- IPC: A61K39/00 ; G16H50/30 ; C07K16/28 ; C07K14/705 ; C12N15/62 ; G01N33/574 ; C07K14/435 ; C07K7/06 ; C07K7/08 ; G01N33/68 ; A61K38/00
Abstract:
The invention provides isolated peptides from the protein EMMPRIN (CD147/Basigin) and antibodies directed against antigenic determinants within said peptides. Pharmaceutical compositions comprising said peptides and antibodies are also disclosed as well as methods of their production and use in vaccination, immunotherapy and diagnosis of proliferative, hyperpermeability, inflammatory, and angiogenesis-related diseases and disorders.
Public/Granted literature
- US20190309031A1 EXTRACELLULAR MATRIX METALLOPROTEINASE INDUCER (EMMPRIN) PEPTIDES AND BINDING ANTIBODIES Public/Granted day:2019-10-10
Information query
