Management of re-synchronization procedures for long term evolution (LTE)/LTE-Advanced (LTE-A) systems with unlicensed spectrum is disclosed. In managing re-synchronization procedures, a base station selects and sends out an enablement indication of the uplink and/or downlink re-synchronization procedure selected. The base station may select the re-synchronization procedures by itself or in coordination with neighboring base stations. Once the indication for the uplink re-synchronization procedure is received at a user equipment (UE), the UE performs its extended clear channel assessment (ECCA) check, but, when the ECCA check is successful, the UE will delay data transmission until the next re-synchronization boundary defined by the selected uplink re-synchronization procedure. With the delayed transmission, the UE performs a clear channel assessment (CCA) check prior to the re-synchronization boundary in order to determine whether the channel is still clear for transmission after the idle period.