Systems and methods are disclosed herein for coordinated selection of a User Plane Function (UPF) in a core network and a Packet Processing Function (PPF) in a radio access network. In some embodiments, a method of operation of network node of a cellular communications network to enable coordinated UPF and PPF selection comprises receiving information indicative of a UPF selected for a protocol data unit session of a wireless device, where the UPF is part of a core network of the cellular communications network. The method further comprises selecting a PPF for the protocol data unit session of the wireless device based on the information indicative of the UPF selected for the protocol data unit session of the wireless device, where the PPF is part of a radio access network of the cellular communications network. In this manner, an optimal routing of user data traffic can be achieved.