Invention Grant
- Patent Title: Antigen specific mRNA cellular cancer vaccines
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Application No.: US15162370Application Date: 2016-05-23
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Publication No.: US11090332B2Publication Date: 2021-08-17
- Inventor: David Koos , Thomas Ichim
- Applicant: Regen Biopharma, Inc
- Applicant Address: US CA La Mesa
- Assignee: Regen Biopharma, Inc
- Current Assignee: Regen Biopharma, Inc
- Current Assignee Address: US CA La Mesa
- Agency: Baumgartner Patent Law
- Agent Marc Baumgartner
- Main IPC: A61K35/15
- IPC: A61K35/15 ; A61K38/10 ; A61K38/16

Abstract:
Disclosed are antigen specific cancer vaccines in which immunogenic epitopes are produced intracellularly by administration of modified mRNA encoding said immunogenic epitopes. In one embodiment of the invention, said modified mRNA encodes peptides derived from the protein survivin. By directly inducing gene expression of the antigens to which an immune response is desired, immunogenic peptides are generated intracellularly, thus allowing for a wider repertoire of epitopes to be presented to the adaptive immune system, which augments likelihood of successful induction of immunity.
Public/Granted literature
- US20170246207A1 ANTIGEN SPECIFIC MRNA CELLULAR CANCER VACCINES Public/Granted day:2017-08-31
Information query
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