Invention Grant
- Patent Title: Filovirus consensus antigens, nucleic acid constructs and vaccines made therefrom, and methods of using same
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Application No.: US16098912Application Date: 2017-05-05
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Publication No.: US11091518B2Publication Date: 2021-08-17
- Inventor: David B. Weiner , Ami Patel , Jian Yan
- Applicant: The Trustees of the University of Pennsylvania , THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY , Inovio Pharmaceuticals, Inc.
- Applicant Address: US PA Philadelphia; US PA Philadelphia; US PA Plymouth Meeting
- Assignee: The Trustees of the University of Pennsylvania,THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY,Inovio Pharmaceuticals, Inc.
- Current Assignee: The Trustees of the University of Pennsylvania,THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY,Inovio Pharmaceuticals, Inc.
- Current Assignee Address: US PA Philadelphia; US PA Philadelphia; US PA Plymouth Meeting
- Agency: Riverside Law LLP
- International Application: PCT/US2017/031215 WO 20170505
- International Announcement: WO2017/192947 WO 20171109
- Main IPC: C07K14/005
- IPC: C07K14/005 ; A61K31/12 ; A61K39/12 ; A61K38/00 ; A61P31/12 ; A61K9/00 ; A61K39/39 ; C07K14/54 ; A61K39/00
Abstract:
Nucleic acid molecules and compositions comprising one or more nucleic acid sequences that encode a consensus Ebolavirus glycoproteinimmunogens are disclosed. The coding sequences optionally include operable linked coding sequence that encode a signal peptide. Immunomodulatory methods and methods of inducing an immune response against Ebolavirus are disclosed. Method of preventing Ebolavirus and methods of treating individuals infected with Ebolavirus are disclosed. Consensus Ebolavirus proteins are disclosed.
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