Invention Grant
- Patent Title: AAV8 mutant capsids and compositions containing same
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Application No.: US16093800Application Date: 2017-04-13
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Publication No.: US11091776B2Publication Date: 2021-08-17
- Inventor: James M. Wilson , Qiang Wang
- Applicant: The Trustees of the University of Pennsylvania
- Applicant Address: US PA Philadelphia
- Assignee: The Trustees of the University of Pennsylvania
- Current Assignee: The Trustees of the University of Pennsylvania
- Current Assignee Address: US PA Philadelphia
- Agency: Howson & Howson LLP
- International Application: PCT/US2017/027392 WO 20170413
- International Announcement: WO2017/180854 WO 20171019
- Main IPC: C12N15/86
- IPC: C12N15/86 ; C07K14/005
Abstract:
Provided herein are AAV8 mutant capsids and rAAV comprising the same. In one embodiment, vectors employing the AAV8 mutant capsid show increased transduction in a selected tissue as compared to AAV8.
Public/Granted literature
- US20190078119A1 NOVEL AAV8 MUTANT CAPSIDS AND COMPOSITIONS CONTAINING SAME Public/Granted day:2019-03-14
Information query
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