Invention Grant
- Patent Title: PRMT5 inhibitors
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Application No.: US16762114Application Date: 2018-11-05
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Publication No.: US11098059B2Publication Date: 2021-08-24
- Inventor: Michelle R. Machacek , David J. Witter , Michael Hale Reutershan , David L. Sloman , Michael D. Altman
- Applicant: Merck Sharp & Dohme Corp.
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Sarah L. Hooson; Catherine D. Fitch
- International Application: PCT/US2018/059131 WO 20181105
- International Announcement: WO2019/094312 WO 20190516
- Main IPC: A61K31/438
- IPC: A61K31/438 ; A61K31/439 ; A61K31/4704 ; C07D498/08 ; C07D401/06 ; C07D401/14 ; C07D453/06

Abstract:
The present invention provides a compound of Formula (I) or the pharmaceutically acceptable salts thereof, which are PRMT5 inhibitors.
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