Invention Grant
- Patent Title: Pegylated endostatin analogue and application thereof
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Application No.: US16349191Application Date: 2017-11-10
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Publication No.: US11098104B2Publication Date: 2021-08-24
- Inventor: Daifu Zhou , Wenchao Wang , Hui Li , Guodong Chang
- Applicant: BEIJING PROTGEN LTD.
- Applicant Address: CN Beijing
- Assignee: BEIJING PROTGEN LTD.
- Current Assignee: BEIJING PROTGEN LTD.
- Current Assignee Address: CN Beijing
- Agency: Klarquist Sparkman, LLP
- Priority: CN201610997233.2 20161110
- International Application: PCT/CN2017/110532 WO 20171110
- International Announcement: WO2018/086603 WO 20180517
- Main IPC: A61K47/00
- IPC: A61K47/00 ; C07K14/78 ; A61K47/58 ; A61K38/00
Abstract:
The present invention provides a polyethylene glycol-modified endostatin analogue and an application thereof. The endostatin analogue is coupled to polyethylene glycol at lysine away from a nucleolin binding domain, or is coupled to polyethylene glycol at lysine away from a nucleolin binding domain and amidogen at the N end.
Public/Granted literature
- US20200270333A1 PEGYLATED ENDOSTATIN ANALOGUE AND APPLICATION THEREOF Public/Granted day:2020-08-27
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