An organic light emitting diode (OLED) display machine with an illumination function is provided. The OLED display machine includes a display region, at least one illumination region, and a drive circuit. An organic light-emitting display device is arranged in the display region. Each illumination region is located at one side edge adjacent to the display region. An organic light-emitting illumination device is disposed in the illumination region. The organic light-emitting illumination device includes a substrate, an insulating layer, a planarization layer, an anode electrode, a light-emitting material layer, and a cathode electrode. The drive circuit is electrically connected to the anode electrode and the cathode electrode of the organic light-emitting illumination device to control an ON or OFF state of the organic light-emitting illumination device. Accordingly, the present invention provides not only a display function, but also illumination, so facilitate wide application and development of the OLED display machine.