A pixel array with a gate driver and a matrix sensor array are provided. The pixel array includes at least one pixel unit and a gate driver. The pixel unit includes a pixel circuit and an open area. The pixel circuit includes a thin film transistor (TFT) and a physical quantity conversion device. The TFT includes gate terminal, source terminal, and drain terminals. The source terminal is coupled to a corresponding data line. The physical quantity conversion device is coupled to the drain terminal of the TFT. The gate driver is disposed in a corresponding pixel unit and a scan line outputted by the gate driver is coupled to the gate terminal in the corresponding pixel unit. The gate driver is disposed adjacent to one of the at least one pixel unit. The gate driver is controlled by a gate control signal to drive the at least one pixel unit.