A cleaning brush is provided. A cleaning unit comprises cleaning beans fixed on a surface of the carrier in a bi-spiral arrangement. The cleaning beans are arranged in an unequally-spaced manner on center of the carrier along a baseline; and, thus, bi-spirals are formed on the center and coiled in two different outward directions. Two annular spiral curve paths are formed with the cleaning beans as coiling the carrier and extending along the two directions. When the carrier cleans an electronic device, a solution or cleaning agent is discharged along the curve paths in spiral tangential directions. Hence, the bi-spiral cleaning unit obtains positive and negative directions on rotating to create a plurality of flow fields. Dirt is discharged easily with water distribution enhanced as compared to unidirectional spiral cleaning devices while a large contact surface, a good cleaning efficiency, and a high decontamination ratio are achieved.