Invention Grant
- Patent Title: Pyridazinones and their use in the treatment of cancer
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Application No.: US15750817Application Date: 2016-08-05
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Publication No.: US11110089B2Publication Date: 2021-09-07
- Inventor: Elias Set Jenö Arnér , William Chester Stafford , Nathan Patrick Coussens , Diane Karen Luci , David Joseph Maloney , Anton Simeonov , Ajit Jadhav , Thomas S. Dexheimer
- Applicant: Elias Set Jenö Arnér , THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES
- Applicant Address: SE Stockholm; US MD Bethesda
- Assignee: Elias Set Jenö Arnér,THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES
- Current Assignee: Elias Set Jenö Arnér,THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES
- Current Assignee Address: SE Stockholm; US MD Bethesda
- Agency: McCarter & English, LLP
- Agent Steven G. Davis; Mei Bai
- Priority: GB1514015 20150807
- International Application: PCT/US2016/045729 WO 20160805
- International Announcement: WO2017/027357 WO 20170216
- Main IPC: C07D413/06
- IPC: C07D413/06 ; A61K31/501 ; A61K45/06

Abstract:
There is provided compounds of formula (I) or pharmaceutically-acceptable salts thereof, wherein W, X, Y, Z, R1, R2 and R3 have meanings provided in the description, which compounds are useful in the treatment of cancers.
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