Invention Grant
- Patent Title: Inhibitors of glucocorticoid receptor
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Application No.: US16065625Application Date: 2016-12-22
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Publication No.: US11110103B2Publication Date: 2021-09-07
- Inventor: Daqing Sun , Lawrence R. McGee , Xiaohui Du , Liusheng Zhu , Xuelei Yan , Yosup Rew , John Eksterowicz , Julio C. Medina , Haiying Zhou , Minna Delarae Balbas , Valeria R. Fantin
- Applicant: ORIC Pharmaceuticals, Inc.
- Applicant Address: US CA South San Francisco
- Assignee: ORIC Pharmaceuticals, Inc.
- Current Assignee: ORIC Pharmaceuticals, Inc.
- Current Assignee Address: US CA South San Francisco
- Agency: Wilson Sonsini Goodrich & Rosati
- International Application: PCT/US2016/068435 WO 20161222
- International Announcement: WO2017/112904 WO 20170629
- Main IPC: C07J41/00
- IPC: C07J41/00 ; A61K31/56 ; A61K31/58 ; A61K31/567 ; A61K45/06 ; C07J1/00 ; C07J21/00 ; C07J43/00
Abstract:
The present invention relates generally to compositions and methods for treating cancer and hypercortisolism. Provided herein are substituted steroidal derivative compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for inhibition of glucocorticoid receptors. Furthermore, the subject compounds and compositions are useful for the treatment of cancer and hypercortisolism.
Public/Granted literature
- US20210023095A1 INHIBITORS OF GLUCOCORTICOID RECEPTOR Public/Granted day:2021-01-28
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