Invention Grant
- Patent Title: Substituted cyclobutylpyridine and cyclobutylpyrimidine compounds as indoleamine 2,3-dioxygenase (IDO) inhibitors
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Application No.: US16753050Application Date: 2018-10-04
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Publication No.: US11111232B2Publication Date: 2021-09-07
- Inventor: Catherine M. White , Abdelghani Achab , Indu T. Bharathan , Xavier Fradera , Yongxin Han , Derun Li , Jongwon Lim , Kun Liu , Meredeth Ann McGowan , Nunzio Sciammetta , Wensheng Yu , Hongjun Zhang , Hua Zhou
- Applicant: MERCK SHARP & DOHME CORP.
- Applicant Address: US NJ Rahway
- Assignee: MERCK SHARP & DOHME CORP.
- Current Assignee: MERCK SHARP & DOHME CORP.
- Current Assignee Address: US NJ Rahway
- Agent Yong Zhao; Anna L. Cocuzzo; Catherine D. Fitch
- International Application: PCT/US2018/054276 WO 20181004
- International Announcement: WO2019/074749 WO 20190418
- Main IPC: A61K31/4418
- IPC: A61K31/4418 ; C07D401/14 ; C07D213/74 ; C07D401/12 ; C07D405/12 ; C07D413/14 ; C07D417/14
Abstract:
Disclosed herein is a compound of formula (I), or a pharmaceutically acceptable salt thereof: Also disclosed herein are uses of a compound disclosed herein in the potential treatment or prevention of an IDO-associated disease or disorder. Also disclosed herein are compositions comprising a compound disclosed herein. Further disclosed herein are uses of a composition in the potential treatment or prevention of an IDO-associated disease or disorder.
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