Invention Grant
- Patent Title: Coumarin derivatives, processes for their preparation and uses thereof for the treatment of cancer
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Application No.: US16648348Application Date: 2018-09-20
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Publication No.: US11111238B2Publication Date: 2021-09-07
- Inventor: Raffaella Di Lucrezia , Tim Bergbrede , Peter Nussbaumer , Uwe Koch , Bert Klebl , Axel Choidas , Anke Unger , Nils-Göran Larsson , Maria Falkenberg-Gustafsson , Claes M. Gustafsson
- Applicant: Lead Discovery Center GmbH , Max Planck Gesellschaft zur Förderung der Wissenschaften e. V. , SOTIO a.s.
- Applicant Address: DE Dortmund; DE Munich; CZ Prague
- Assignee: Lead Discovery Center GmbH,Max Planck Gesellschaft zur Förderung der Wissenschaften e. V.,SOTIO a.s.
- Current Assignee: Lead Discovery Center GmbH,Max Planck Gesellschaft zur Förderung der Wissenschaften e. V.,SOTIO a.s.
- Current Assignee Address: DE Dortmund; DE Munich; CZ Prague
- Agency: Kagan Binder, PLLC
- Priority: EP17001565 20170920
- International Application: PCT/EP2018/075473 WO 20180920
- International Announcement: WO2019/057821 WO 20190328
- Main IPC: A61K45/06
- IPC: A61K45/06 ; C07D413/14 ; C07D311/18 ; C07D405/12 ; C07D409/04 ; C07D409/14 ; C07D491/052
Abstract:
The invention provides novel coumarin derivatives as specific mitochondrial RNA polymerase inhibitors for the treatment of cancer.
Public/Granted literature
- US20200291011A1 COUMARIN DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND USES THEREOF FOR THE TREATMENT OF CANCER Public/Granted day:2020-09-17
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