Invention Grant
![Pyrrolo[2,3-d]pyrimidinyl, pyrrolo[2,3-b]pyrazinyl and pyrrolo[2,3-d]pyridinyl acrylamides](/docs/US/2021-09-07/US11111242B2/abs.jpg.600x600.jpg)
- Patent Title: Pyrrolo[2,3-d]pyrimidinyl, pyrrolo[2,3-b]pyrazinyl and pyrrolo[2,3-d]pyridinyl acrylamides
-
Application No.: US15446500Application Date: 2017-03-01
-
Publication No.: US11111242B2Publication Date: 2021-09-07
- Inventor: Atli Thorarensen , Matthew Frank Brown , Agustin Casimiro-Garcia , Ye Che , Jotham Wadsworth Coe , Mark Edward Flanagan , Adam Matthew Gilbert , Matthew Merrill Hayward , Jonathan David Langille , Justin Ian Montgomery , Jean-Baptiste Telliez , Rayomand Jal Unwalla , John I. Trujillo
- Applicant: Pfizer Inc.
- Applicant Address: US NY New York
- Assignee: Pfizer Inc.
- Current Assignee: Pfizer Inc.
- Current Assignee Address: US NY New York
- Agent A. David Joran
- Main IPC: A61K31/4523
- IPC: A61K31/4523 ; C07D471/04 ; C07D471/08 ; C07D487/04 ; C07D487/10 ; C07D498/04
![Pyrrolo[2,3-d]pyrimidinyl, pyrrolo[2,3-b]pyrazinyl and pyrrolo[2,3-d]pyridinyl acrylamides](/abs-image/US/2021/09/07/US11111242B2/abs.jpg.150x150.jpg)
Abstract:
The present invention provides pharmaceutically active pyrrolo[2,3-d]pyrimidinyl and pyrrolo[2,3-d]pyridinyl acrylam ides and analogues thereof, having the structure: or a pharmaceutically acceptable salt thereof, as set forth in the Description. Such compounds are useful for inhibiting Janus Kinase (JAK). This invention also is directed to compositions comprising methods for making such compounds, and methods for treating and preventing conditions mediated by JAK.
Public/Granted literature
- US20170247372A1 PYRROLO[2,3-D]PYRIMIDINYL, PYRROLO[2,3-B]PYRAZINYL AND PYRROLO[2,3-D]PYRIDINYL ACRYLAMIDES Public/Granted day:2017-08-31
Information query
IPC分类:
