- Patent Title: Nitrogen-containing macrocyclic conjugates as radiopharmaceuticals
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Application No.: US16712485Application Date: 2019-12-12
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Publication No.: US11111254B2Publication Date: 2021-09-07
- Inventor: Paul Stephen Donnelly , Michelle Therese Ma , Denis Bernard Scanlon
- Applicant: The University of Melbourne
- Applicant Address: AU Victoria
- Assignee: The University of Melbourne
- Current Assignee: The University of Melbourne
- Current Assignee Address: AU Victoria
- Agency: McBee Moore & Vanik IP LLC
- Priority: AU2008906239 20081202
- Main IPC: A61K8/72
- IPC: A61K8/72 ; C07D521/00 ; A61K51/04 ; A61K51/08 ; A61K49/10 ; A61K49/08 ; A61K49/06 ; A61K51/00 ; A61K51/02 ; A61K51/10
Abstract:
The present invention relates to compounds that are useful as metal ligands and which either contain a molecular recognition moiety or can be bound to a molecular recognition moiety and methods of making these compounds. Once the compounds that contain a molecular recognition moiety are coordinated with a suitable metallic radionuclide, the coordinated compounds are useful as radiopharmaceuticals in the areas of radiotherapy and diagnostic imaging. The invention therefore also relates to methods of diagnosis and therapy utilising the radiolabelled compounds of the invention.
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