• Patent Title: Morphic forms of 4-amino-7-(3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-methyl-7H-pyrrolo[2,3-d]pyrimidine-5-carboxamide and uses thereof
  • Application No.: US16645876
    Application Date: 2018-09-21
  • Publication No.: US11111264B2
    Publication Date: 2021-09-07
  • Inventor: Roy W. WareVenkat LakshmananAaron Leigh Downey
  • Applicant: Chimerix, Inc.
  • Applicant Address: US NC Durham
  • Assignee: Chimerix, Inc.
  • Current Assignee: Chimerix, Inc.
  • Current Assignee Address: US NC Durham
  • Agency: Cooley LLP
  • Agent Heidi A. Erlacher; Gabriel Magallanes
  • International Application: PCT/US2018/052180 WO 20180921
  • International Announcement: WO2019/060692 WO 20190328
  • Main IPC: C07H19/14
  • IPC: C07H19/14
Morphic forms of 4-amino-7-(3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-methyl-7H-pyrrolo[2,3-d]pyrimidine-5-carboxamide and uses thereof
Abstract:
The present disclosure relates to crystalline morphic forms of 4-amino-7-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl) tetrahydrofuran-2-yl)-2-methyl-7H-pyrrolo[2,3-d]pyrimidine-5-carboxamide. The morphic form can be a stable hemihydrate crystalline form.
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